Datasets
2021
Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancers.
Mawla AM, van der Meulen T, Huising MO.
BMC Genomics 24, 202.
2019
Navigating the Depths and Avoiding the Shallows of Pancreatic Islet Cell Transcriptomes.
Mawla AM, Huising MO.
Diabetes, 68(7): 1380-1393.
2017
Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
van der Meulen T, Mawla AM, DiGruccio MR, Adams MW, Nies V, Dólleman S, Liu S, Ackermann AM, Cáceres E, Hunter AE, Kaestner KH, Donaldson CJ, Huising MO.
Cell Metabolism, 25(4):911-926.
2016
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.
DiGruccio MR, Mawla AM, Donaldson CJ, Noguchi GM, Vaughan J, Cowing-Zitron C, van der Meulen T, Huising MO.
Molecular Metabolism, 5(7):449–458.
2015
Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion.
van der Meulen T, Donaldson CJ, Caceres E, Hunter AE, Cowing-Zitron C, Pound LD, Adams MW, Zembrzycki A, Grove KL, Huising MO.
Nature Medicine, 21(7):769-776.
2014
The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.
Benner C, van der Meulen T, Caceres E, Tigyi K, Donaldson CJ, Huising MO.
BMC Genomics 15(1):620.